Companies are the main forces that drive an economy toward economic growth. Innovation encourages competitiveness within firms, and at the same time builds the conditions for it to happen. One of the most determinant factors of competitiveness is the teams workforce. As the world becomes more and more global, firms are working worldwide, under economies that are moving towards creating products and services with higher added value. Innovation management within the firms requires a particular vision on \"global teams\". How will they go about the innovations? How will they be handle knowledge management? What are the transfer knowledge and learning rules for communities and workforces? How will the data analysed from global companies and different cultures be supported? The central hypothesis of this research has been focused on this particular approach: \"The management of Global Companies needs to work on solving innovation basal factors to be successful in the search for managing a global workforce\". So the challenge is to implement innovation processes that stress the focus on data support, cultural alignment and developing strong capabilities for the high performance workforce to create new value. The present paper identified, through the analysis of eight multinational companies, factors that determine the success of competitive strategy and innovation in global companies. We worked with an open-ended interview methodology and selected firms based on three specific criteria. By way of research results, we worked developing a model for managing innovation including the factors identified as success promoters: i) Cultural Strategic Alignment through the value chain, ii) Standardization of Processes along entire value chain, iii) Transversal strategic management indicators throughout the entire organization. iv) Incorporation of technological tools for collaboration. In fact, we can conclude that global firms need to address innovation management among their tools to strengthen their innovation processes like: knowledge management, learning process and feedback, human resources and global workforce, productive chains, and management of their core competence and complementary assets.